Jeuveau, like BOTOX®, uses purified botulinum toxin to temporarily relax the small muscle groups that cause dynamic wrinkles. When these compounds are injected into muscle tissue, they block nerve signals so that the brain can no longer instruct treated muscles to move. Though they work similarly, Jeuveau and BOTOX® are made by different manufacturers and produced in different countries.
BOTOX® is made by Allergan and manufactured in Ireland, whereas Jeuveau is made by Evolus and produced in South Korea. Jeuveau also uses a slightly different form of botulinum toxin than BOTOX®: BOTOX® contains onabotulinumtoxinA and Jeuveau contains prabotulinumtoxinA. According to clinical trials, both compounds share a similar safety profile and are equally effective for treating dynamic wrinkles.